Author

Leighanne A. Brammer Basta

Johns Hopkins UniversityORCID 0000-0002-4121-5505Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1 Organism:yeast· 1

Frequent Co-Authors

Ally Moyer· 1 shared Ananya NaickiD· 1 shared Anthony D’Amato· 1 shared Anthony Staiti· 1 shared Antonio Spina· 1 shared Arden Snee· 1 shared Ardeshir Kianercy· 1 shared Brendan R. CamellatoiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperSynthetic Biology

Ally Moyer

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2 papers

Recent·Most cited

A Peptide-Based Assay for Profiling Activity and Inhibitors of Mycobacterial L,D-Transpeptidases

Karl L. Ocius, Rachel E. Sanborn, Ananya Naick, Leighanne A. Brammer Basta, Marcos M. Pires

This paper develops a high-throughput peptide-based assay to profile L,D-transpeptidase activity and inhibitors in mycobacteria, showing potent inhibition by (carba)penems.

bioRxiv · Feb 6, 2026 · PreprintBiochemistry

Manipulating the 3D organization of the largest synthetic yeast chromosome

Weimin Zhang, Luciana Lazar‐Stefanita, Hitoyoshi Yamashita, Michael J. Shen, LESLIE ANN MITCHELL, Hikaru Kurasawa, Evgenii Lobzaev, Viola Fanfani, Max A. B. Haase, Xiaoji Sun, Qingwen Jiang, Gregory W. Goldberg, David M. Ichikawa, Stephanie L. Lauer, Laura H. McCulloch, , Jef D. Boeke

This paper synthesizes the largest eukaryotic yeast chromosome, synIV, and investigates how its 3D structure affects gene regulation and transcription.

Molecular Cell · Nov 8, 2023Peer-reviewedSynthetic Biology