Author

Xiaoji Sun

NYU Langone HealthORCID 0000-0002-2365-0888Unclaimed ORCID profile · follow to get notified of new preprints

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Xiaoji Sun1 paper

Biology Disciplines

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Synthetic Biology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:yeast· 3 Research Focus:gene regulatory network inference· 2 Assay:whole-genome sequencing· 2 Assay:DNA methylation· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Andreas HochwageniD· 2 shared Giovanni StracquadanioiD· 2 shared Hong Seo LimiD· 2 shared Jef D. BoekeiD· 2 shared Jitong Cai· 2 shared Joel S. BaderiD· 2 shared Jonna Heldrich· 2 shared Ju Young AhniD· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersSynthetic Biology

Andreas HochwagenORCID

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3 papers

Recent·Most cited

Manipulating the 3D organization of the largest synthetic yeast chromosome

Weimin Zhang, Luciana Lazar‐Stefanita, Hitoyoshi Yamashita, Michael J. Shen, LESLIE ANN MITCHELL, Hikaru Kurasawa, Evgenii Lobzaev, Viola Fanfani, Max A. B. Haase, Xiaoji Sun, Qingwen Jiang, Gregory W. Goldberg, David M. Ichikawa, Stephanie L. Lauer, Laura H. McCulloch, , Jef D. Boeke

This paper synthesizes the largest eukaryotic yeast chromosome, synIV, and investigates how its 3D structure affects gene regulation and transcription.

Molecular Cell · Nov 8, 2023Peer-reviewedSynthetic Biology

Synthetic chromosome fusion: effects on genome structure and function

Jingchuan Luo, Luís A. Vale-Silva, Adhithi R. Raghavan, Guillaume Mercy, Jonna Heldrich, Xiaoji Sun, Mingyu Kenneth Li, Weimin Zhang, Neta Agmon, Kun Yang, Jitong Cai, Giovanni Stracquadanio, Agnès Thierry, Yu Zhao, Camila Coelho, , Jef D. Boeke

The paper synthesizes a shorter yeast chromosome and studies its fusion with other chromosomes, revealing new 3D structural interactions and Red1 binding patterns.

bioRxiv · Aug 10, 2023 · PreprintSynthetic Biology

Topoisomerases modulate the timing of meiotic DNA breakage and chromosome morphogenesis in Saccharomyces cerevisiae

Jonna Heldrich, Xiaoji Sun, Luís A. Vale-Silva, Tovah E. Markowitz, Andreas Hochwagen

This study investigates the roles of topoisomerases I and II in meiotic DNA breakage and chromosome remodeling in yeast, showing distinct effects of their disruption on DSB timing and chromosome structure.

Genetics · Mar 9, 2020Peer-reviewedGenomics