Author

Pedro Casado

Queen Mary University of LondonORCID 0000-0002-4207-9349Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Organism:human· 4 Research Focus:differential expression· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

Pedro R. CutillasiD· 4 shared Vinothini RajeeveiD· 3 shared Alun Parsons· 2 shared Ana Rio‐MachíniD· 2 shared Caroline Akemi HeckmaniD· 2 shared Csaba BödöriD· 2 shared Findlay Bewicke‐CopleyiD· 2 shared John G. GribbeniD· 2 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Focal author (center)Selected co-authorORCID co-authorUnlinked name

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4 shared papersCancer Biology

Pedro R. CutillasORCID

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Author profile →

4 papers

Recent·Most cited

Greatwall Kinase regulates Acute Myeloid Leukaemia Cell Division through a Non-Canonical Mechanism

Sandra M. Martín‐Guerrero, Tommy Shields, Pedro Casado, Róbert Zach, Vinothini Rajeeve, Nadia Afroz-Nishat, Irbaz I. Badshah, Megan Meredith, William R. Foster, Helfrid Hochegger, Pedro R. Cutillas

This study shows Greatwall kinase regulates AML cell division through a non-canonical pathway distinct from its role in solid tumors.

EMBO Reports · Sep 30, 2026Peer-reviewedCell Biology

β3-Integrin controls pericyte metabolic states and shapes tumour-stromal metabolic crosstalk in breast cancer

Elien Heylen, Alex Jordan, Katie Baird, Gabriela D’Amico, Vimala Anthonydhason, Valle Morales, Vinothini Rajeeve, Pedro Casado, Pedro R. Cutillas, Tarek Abdelfatah, Katiuscia Bianchi, Kairbaan Hodivala‐Dilke

This study identifies two β3-integrin-dependent metabolic states in pericytes and shows their impact on tumour-stromal metabolic interactions in breast cancer.

bioRxiv · Sep 25, 2026 · PreprintCancer Biology

DEK::NUP214 acts as an XPO1-dependent transcriptional activator of essential leukemia genes

Fadimana Kaya, Findlay Bewicke‐Copley, Juho Jalmari Miettinen, Pedro Casado, Eve Leddy, Özgen Deniz, Vincent‐Philippe Lavallée, Céline Philippe, Jiexin Zheng, Florian Grebien, Naeem Khan, Szilvia Krizsán, Joseph J Saad, Alexis Nolin-Lapalme, Josée Hébert, , Ana Rio‐Machín

This study identifies DEK::NUP214 as an XPO1-dependent transcriptional activator of leukemia genes, showing selective response to XPO1 inhibitors in t(6;9) AML cases.

Leukemia · Apr 9, 2025Peer-reviewedCancer Biology

Integrative phosphoproteomics defines two biologically distinct groups of KMT2A rearranged acute myeloid leukaemia with different drug response phenotypes

Pedro Casado, Ana Rio‐Machín, Juho Jalmari Miettinen, Findlay Bewicke‐Copley, Kevin Rouault‐Pierre, Szilvia Krizsán, Alun Parsons, Vinothini Rajeeve, Farideh Miraki‐Moud, David Christopher Taussig, Csaba Bödör, John G. Gribben, Caroline Akemi Heckman, Jude Fitzgibbon, Pedro R. Cutillas

The paper identifies two distinct subgroups of KMT2A-rearranged AML using phosphoproteomics and shows different drug response profiles.

Signal Transduction and Targeted Therapy · Feb 26, 2023Peer-reviewedMolecular Biology