Giovanni de Nola

HiExM enables scalable single-organelle analysis by improving spatial resolution and throughput, allowing detailed profiling of late endosomes and lysosomes.

This study shows that ionic exposure history affects inner nuclear membrane voltage and chromatin texture in NRK cells, with responses dependent on exposure order and chromatin state.

This paper develops a label-free imaging platform to study nucleolar dynamics and metabolic shifts in tissues, revealing NADH depletion under nucleolar stress and progesterone-induced changes in endometrial organoids.

This study develops magnetoelectric nanodiscs (MENDs) for wireless, transgene-free neuromodulation, showing they can control reward behavior in mice through magnetic field stimulation.

The paper identifies Ribosome-Associated Vesicles (RAVs) as dynamic platforms that facilitate activity-dependent local translation in neurons by transporting ribosomes to distal processes.

The paper identifies distinct molecular machineries for Ca2+ channel clustering and synaptic vesicle priming at active zones, showing that Liprin- and PTPσ specifically support priming site assembly.

The paper investigates whether Munc13 supports vesicle fusogenicity independently of active zone scaffolds and synaptic vesicle docking.

The paper investigates active zone functions by knocking out RIM+ELKS and reconstituting key processes, showing that docking and fusion competence are separable and scaffolding is not required for release.

This study shows phosphorylation of Liprin-3 triggers phase separation to regulate presynaptic active zone structure and function.

This study investigates the role of LAR-RPTPs in synapse structure and function by analyzing triple knockout mice, finding they are dispensable for presynaptic organization and function.