Author

Deborah Koltai Attix

Duke UniversityORCID 0000-0002-4254-9902Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:GWAS / association mapping· 4 Assay:GWAS summary statistics· 4 Organism:human· 4 Approach:statistical model· 4 Research Focus:fine-mapping· 1 Research Focus:polygenic risk· 1

Frequent Co-Authors

Alex Hatzimanolis· 4 shared Andrea Christoforou· 4 shared Antony PaytoniD· 4 shared David C M LiewaldiD· 4 shared Derek W. MorrisiD· 4 shared Dimitrios AvramopoulosiD· 4 shared Dwight DickinsoniD· 4 shared Eliza L. CongdoniD· 4 shared

Activity by Year

2017-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersGenetics

Alex Hatzimanolis

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4 papers

Recent·Most cited

Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways

Max Lam, William David Hill, Joey W. Trampush, Jin Yu, Emma Knowles, Gail Davies, Eli A. Stahl, Laura M. Huckins, David C M Liewald, Srdjan Djurovic, Ingrid Melle, Kjetil S. Sundet, Andrea Christoforou, Ivar Reinvang, Pamela DeRosse, , Todd Lencz

The paper uses pleiotropic meta-analysis to identify genetic loci associated with cognition, education, and schizophrenia, revealing distinct biological mechanisms for concordant and discordant genetic correlations.

The American Journal of Human Genetics · Aug 1, 2019Peer-reviewedGenetics

GWAS meta-analysis (N=279,930) identifies new genes and functional links to intelligence

Jeanne E. Savage, Philip R. Jansen, Sven Stringer, Kyoko Watanabe, Julien Bryois, Christiaan de Leeuw, Mats Nagel, Swapnil Awasthi, Peter B. Barr, Jonathan R. I. Coleman, Katrina L. Grasby, Anke R. Hammerschlag, Jakob André Kaminski, Robert Karlsson, Eva M. L. Krapohl, , Lene Christiansen

This study identifies 206 new genomic loci and 1,041 genes associated with intelligence using a large GWAS meta-analysis of 279,930 individuals.

Nature Genetics · Jun 25, 2018Peer-reviewedGenetics

Ninety-nine independent genetic loci influencing general cognitive function include genes associated with brain health and structure (N = 280,360)

Gail Davies, Max Lam, Sarah E. Harris, Joey W. Trampush, Michelle Luciano A, William David Hill, Saskia P. Hagenaars, Stuart James Ritchie, Riccardo Emilio Marioni, Chloe Fawns‐Ritchie, David C M Liewald, Judith A. Okely, Ari Ahola‐Olli, Catriona L. K. Barnes, Lars Bertram, , Luca Kleineidam

This study identifies 99 genetic loci associated with general cognitive function using data from 280,360 individuals, finding genes linked to brain structure and neurodegenerative disorders.

Nature Communications · May 22, 2018Peer-reviewedGenetics

Large-Scale cognitive GWAS Meta-analysis Reveals Tissue-Specific Neural Expression and Potential Nootopic Drug Targets

Max Lam, Joey W. Trampush, Jin Yu, Emma Knowles, Gail Davies, David C M Liewald, John M. Starr, Srdjan Djurovic, Ingrid Melle, Kjetil S. Sundet, Andrea Christoforou, Ivar Reinvang, Pamela DeRosse, Astri Johansen Lundervold, Vidar Martin Steen, , Todd Lencz

This study performs a large-scale GWAS of cognitive ability, identifies 70 genomic loci, and finds tissue-specific gene expression and potential drug targets.

Cell Reports · Nov 1, 2017Peer-reviewedGenomics