Chloe Fawns‐Ritchie

The paper develops epigenetic scores for GDF15 and NT-proBNP levels, showing associations with disease risks and brain health traits in two cohorts.

The paper develops epigenetic scores (EpiScores) for plasma proteins to predict disease risk, finding 137 associations with incident morbidities independent of known factors.

This study identifies genetic loci associated with SARS-CoV-2 susceptibility and disease severity using GWAS and colocalization, and links them to eQTLs in various tissues.

The paper uses symptom-based case predictions to conduct a GWAS on COVID-19, finding new genetic susceptibility insights and suggesting different genetic architectures for severity and susceptibility.

This study identifies lipid biomarkers associated with brain structure but not cognitive ability in older adults using metabolomic data from the LBC1936 cohort.

This study identifies brain structure correlates of general intelligence using UK Biobank data, finding stronger associations in older adults and specific brain regions linked to intelligence.

This study examines associations between vascular risk factors and brain MRI indices in UK Biobank, finding that higher vascular risk is linked to poorer brain health across macro- and microstructural measures.

This study examines the association between polygenic risk scores for neurodegenerative disorders and cognitive performance, finding lower cognitive performance with higher risk scores for AD, ALS, and FTD.

This study identifies 99 genetic loci associated with general cognitive function using data from 280,360 individuals, finding genes linked to brain structure and neurodegenerative disorders.

The paper identifies 116 independent genetic variants associated with neuroticism in over 329,000 UK Biobank participants and finds genetic correlations with mental health traits.