Author

Daniel D. Child

University of WashingtonORCID 0000-0002-4309-0144Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Assay:spatial transcriptomics· 2 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Caitlin S. LatimeriD· 2 shared Aliza Ben-Varon· 1 shared Amanda KirklandiD· 1 shared Amber NolaniD· 1 shared Andrea Compton· 1 shared Angela M. WilsoniD· 1 shared Anya Gemos· 1 shared Bereket Z. Gidi· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersNeuroscience

Caitlin S. LatimerORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Multimodal spatial transcriptomics determines repeat expansion, huntingtin aggregation, and selective cortical neuron loss in Huntington Disease

Sonia Vazquez‐Sanchez, Olatz Arnold-García, Carlos Chillón-Marinas, Roy Maimon, Jie Cui, Katelyn McNair, Yuanyi Dai, Norma Martínez Jiménez, Daniel D. Child, Leslie Michels Thompson, Jone López‐Erauskin, Bogdan Bintu, Don W. Cleveland

This paper develops a multimodal spatial transcriptomics approach to study CAG repeat expansion, huntingtin aggregation, and neuron loss in Huntington's Disease using human brain tissue.

Cell · Oct 1, 2026Peer-reviewedNeuroscience

Single nucleus RNA sequencing and spatial transcriptomics reveal unique functionalities of gray matter versus white matter oligodendrocytes in aging and Alzheimer's Disease

Joseph P. Voth, Javier A. Ramos Benitez, Angela M. Wilson, Scott R. Kennedy, Mamatha Damodarasamy, Amanda Kirkland, Jeremy A. Miller, Caitlin S. Latimer, Emily Ragaglia, Amber Nolan, Daniel D. Child, Lisa M. Keene, Cindy Reichel, Brendan F. Kohrn, Larry S. Sherman, , C. Dirk Keene

The paper uses single-nucleus RNA sequencing and spatial transcriptomics to compare oligodendrocyte functions in gray and white matter across aging and Alzheimer's Disease.

bioRxiv · Sep 3, 2026 · PreprintNeuroscience

Atrophin-1 Antisense Oligonucleotide Provides Robust Protection from Pathology in a Fully Humanized DRPLA Model

Velvet L. Smith, Bereket Z. Gidi, Robert M. Bragg, Jeffrey P. Cantle, Aliza Ben-Varon, Briana Noble, Sílvia Prades, Andrea Compton, Julie Greenfield, Joanna A. Korecka, Anya Gemos, Timothy W. Yu, Vikram Khurana, Holly B. Kordasiewicz, Hien Tran Zhao, , Jeffrey B. Carroll

This paper demonstrates that antisense oligonucleotides targeting human ATN1 protect against DRPLA pathology in a fully humanized mouse model.

Molecular Therapy — Nucleic Acids · Dec 31, 2025Peer-reviewedNeuroscience

A familial missense variant in the Alzheimer's Disease gene SORL1 impairs its maturation and endosomal sorting.

Elnaz Fazeli, Daniel D. Child, Stephanie A. Bucks, Miki Stovarsky, Gabrielle Edwards, Shannon E. Rose, Chang‐En Yu, Caitlin S. Latimer, Yu Kitago, Thomas D. Bird, Suman Jayadev, Olav M. Andersen, Jessica E. Young

The paper identifies a pathogenic SORL1 variant, p.R953C, associated with Alzheimer's Disease and shows it impairs protein maturation and endosomal sorting.

Acta Neuropathologica · Jan 20, 2024Peer-reviewedNeuroscience