Mateusz Maciej Wagner

This study identifies Kcs1-dependent inositol pyrophosphates as regulators of DNA repair via Pho80-Pho85 in budding yeast, independent of homologous recombination.

The paper reports crystal structures of LlaI components, revealing nucleotide specificity evolution and DNA binding mechanisms in McrBC restriction complexes.

This paper introduces ProKAS, a proteomic platform for spatial and quantitative analysis of kinase activity using mass spectrometry, and demonstrates its application in studying DNA damage response kinases.

The paper introduces PROMIS, a co-fractionation mass spectrometry technique integrated with chromatographic methods to map protein-metabolite interactions in E. coli, identifying 994 interactions and revealing novel functional insights.

The paper develops a system for mitosis-specific protein recruitment to the plasma membrane using a phosphorylation-controlled switch, without exogenous triggers.

MAGMa is a tool for differential expression analysis in mass-spectrometry proteomic data, showing improved sensitivity and specificity in detecting true signals.

This study identifies how Mec1/ATR kinase controls homologous recombination to suppress gross chromosomal rearrangements through Rad53 and Sgs1 pathways.