Author

Nicolò Coianiz

University of ZurichORCID 0000-0002-4357-0359Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:flow cytometry· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Alperen AcariiD· 1 shared Anne EugsteriD· 1 shared Benjamin KasendaiD· 1 shared Christoph SchultheißiD· 1 shared Claudia FischeriD· 1 shared Corinne C. WidmeriD· 1 shared Dominik Heim· 1 shared Emma ReynaudiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperImmunology

Alperen AcariORCID

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2 papers

Recent·Most cited

IGLV3-21-R110-directed bispecific antibodies activate T cells and promote killing in a high-risk subset of chronic lymphocytic leukemia

Claudia Fischer, Shih‐Shih Chen, Johanna Nimmerfroh, Anne Eugster, Simon Stücheli, Christoph Schultheiß, Corinne C. Widmer, Dominik Heim, Benjamin Kasenda, Jakob Robert Passweg, Sebastian Kobold, Lukas Egli, Nicolò Coianiz, Obinna Chijioke, Nicholas Chiorazzi, , Mascha Binder

This study develops bispecific antibodies targeting IGLV3-21R110 to selectively kill high-risk CLL cells while sparing healthy B cells and stem cells.

Haematologica · Sep 11, 2025Peer-reviewedCancer Biology

Comprehensive immune profiling of melanoma-draining lymph nodes identifies plasmacytoid dendritic cells as new biomarker for PD-L1 blockade

Emma Reynaud, Sonya Belherazem, Özge Cicek Sener, Sarah Hofmann, Alperen Acari, Pragati Lodha, Shruthi Hemanna, Nicolò Coianiz, Volker Ast, Sònia Tugues, Lothar C. Dieterich

The paper identifies plasmacytoid dendritic cells (pDCs) in tumor-draining lymph nodes as a potential biomarker for predicting response to PD-L1 blockade therapy in melanoma.

bioRxiv · Aug 22, 2025 · PreprintImmunology