Author

Sarah Hofmann

Brigham and Women's HospitalORCID 0000-0002-6115-5239Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Assay:flow cytometry· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Adrian Higginbottom· 1 shared Alperen AcariiD· 1 shared Aviad SianyiD· 1 shared Beata Toth Cohen· 1 shared Chen EitaniD· 1 shared Claire Louise RiggsiD· 1 shared Daoud Sheban· 1 shared Emma ReynaudiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperMolecular Biology

Adrian Higginbottom

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2 papers

Recent·Most cited

Comprehensive immune profiling of melanoma-draining lymph nodes identifies plasmacytoid dendritic cells as new biomarker for PD-L1 blockade

Emma Reynaud, Sonya Belherazem, Özge Cicek Sener, Sarah Hofmann, Alperen Acari, Pragati Lodha, Shruthi Hemanna, Nicolò Coianiz, Volker Ast, Sònia Tugues, Lothar C. Dieterich

The paper identifies plasmacytoid dendritic cells (pDCs) in tumor-draining lymph nodes as a potential biomarker for predicting response to PD-L1 blockade therapy in melanoma.

bioRxiv · Aug 22, 2025 · PreprintImmunology

Spatio-temporal Proteomic Analysis of Stress Granule disassembly using APEX Reveals Regulation by SUMOylation and links to ALS pathogenesis

Hagai Marmor-Kollet, Aviad Siany, Nancy Kedersha, Naama Knafo, Natalia Rivkin, Yehuda Matan Danino, Thomas G. Moens, Tsviya Olender, Daoud Sheban, Nir Cohen, Tali Dadosh, Yoseph Addadi, Revital Ravid, Chen Eitan, Beata Toth Cohen, , Eran Hornstein

This study uses APEX proximity-proteomics to analyze the spatio-temporal proteomic changes during stress granule disassembly, identifying novel proteins and revealing SUMOylation's role in ALS pathogenesis.

Molecular Cell · Nov 19, 2020Peer-reviewedMolecular Biology