Author

Martín Villalba

InsermORCID 0000-0002-4385-4888Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1 Organism:zebrafish· 1

Frequent Co-Authors

Delphine GitenayiD· 2 shared Guillaume BossisiD· 2 shared Loïs CoënoniD· 2 shared Marion de ToledoiD· 2 shared Sara ZemitiiD· 2 shared Alberto AneliD· 1 shared Amel Bouzid· 1 shared Ana Bellia Aznar· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

Delphine GitenayORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Metabolic rewiring of cancer cells induces metastasis via ERK5 but triggers recognition by NK cells

Sara Zemiti, Steffy Escayg, Benjamin Hay, Amel Bouzid, Catherine Alexia, Carine Jacquard, Noemie Dudzinska, Ananya Sen, Jose Prudenciano, Daouda Abba Moussa, Michael Constantinides, Loïs Coënon, Nerea Allende-Vega, Mauricio Campos‐Mora, Sabine Gerbal‐Chaloin, , Delphine Gitenay

This study shows that metabolic rewiring via fatty acid oxidation promotes cancer metastasis but also enhances NK cell recognition and killing of metastatic cells.

bioRxiv · Aug 26, 2025 · PreprintCancer Biology

The SUMOylation inhibitor TAK-981 (Subasumstat) triggers IFN-I-dependent activation of Natural Killer cells against Acute Myeloid Leukemias.

Rawan Hallal, Marion de Toledo, Denis Tempé, Rayane Berrahouane, Sara Zemiti, Loïs Coënon, Delphine Gitenay, Simon George, Moritz Schüssler, Nadine Laguette, Sarah Bonnet, Ludovic Gabellier, Guillaume Cartron, Mireia Pelegrín, Martín Villalba, Guillaume Bossis

This paper shows that TAK-981 activates NK cells against AML by inducing IFN-I secretion, enhancing their cytotoxicity and cytokine production.

Molecular Cancer Therapeutics · Jul 15, 2025Peer-reviewedCancer Biology