Author

Sylvie Callegari

The University of MelbourneORCID 0000-0002-4402-945XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1 Organism:human· 1

Frequent Co-Authors

Alexandra L. GarnhamiD· 1 shared Amali CoorayiD· 1 shared Andreas StrasseriD· 1 shared Andrew H. WeiiD· 1 shared Andrew J. KuehiD· 1 shared Andrew P. LeisiD· 1 shared Angela BoshnakovskaiD· 1 shared Annabella ThomasiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperCancer Biology

Alexandra L. GarnhamORCID

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3 papers

Recent·Most cited

Transcriptomic alterations including p53 pathway dysregulation prime DNMT3A mutant cells for transformation

Erin Lawrence, Amali Cooray, Andrew J. Kueh, Martin Pál, Lin Tai, Alexandra L. Garnham, Connie S.N. Li Wai Suen, Hannah Kate Vanyai, Quentin A. Gouil, James Lancaster, Sylvie Callegari, Lauren Whelan, Elizabeth Lieschke, Annabella Thomas, Andreas Strasser, , Marco J. Herold

This study shows DNMT3A mutations reduce DNA methylation and disrupt p53 pathway, increasing self-renewal and cancer risk in hematopoietic cells.

EMBO Reports · Apr 30, 2025Peer-reviewedCancer Biology

Profiling the LAM family of contact site tethers provides insights into their regulation and function

Emma J. Fenech, Meital Kupervaser, Angela Boshnakovska, Shani Ravid, Inês Gomes Castro, Yeynit Asraf, Sylvie Callegari, Christof Lenz, Henning Urlaub, Peter Rehling, Maya Schuldiner

The paper profiles the LAM family of contact site tethers to understand their localization and function, revealing unique and shared roles through proximity labeling.

bioRxiv · Apr 18, 2024Cell Biology

Interaction of PINK1 with nucleotides and kinetin

Zhong Yan Gan, Sylvie Callegari, Thanh Ngoc Nguyen, Nicholas S. Kirk, Andrew P. Leis, Michael Lazarou, Grant Dewson, David Komander

The paper investigates PINK1's interaction with nucleotides and kinetin, revealing structural changes and binding constraints that affect its activity and mitophagy.

Science Advances · Jan 19, 2024Peer-reviewedMolecular Biology