Author

Melissa Sanchez

Howard Hughes Medical InstituteORCID 0000-0002-4403-3977Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1

Frequent Co-Authors

Jenni DurieuxiD· 2 shared Melissa G. MetcalfiD· 2 shared Samira MonshietehadiiD· 2 shared Amelia FarinasiD· 1 shared Andrew Dillin· 1 shared Andrew G. DilliniD· 1 shared Arushi SahayiD· 1 shared Ashley E. FrakesiD· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersNeuroscience

Jenni DurieuxORCID

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2 papers

Recent·Most cited

Cell non-autonomous control of autophagy and metabolism by glial cells

Melissa G. Metcalf, Samira Monshietehadi, Arushi Sahay, Jenni Durieux, Ashley E. Frakes, Martina Velichkovska, Cesar Mena, Amelia Farinas, Melissa Sanchez, Andrew G. Dillin

This study shows glial cells control autophagy and metabolism in C. elegans through non-autonomous activation of HLH-30 in the intestine.

iScience · Feb 27, 2024Peer-reviewedNeuroscience

A non-canonical arm of UPRER mediates longevity through ER remodeling and lipophagy.

Joseph R. Daniele, Ryo Higuchi-Sanabria, Vidhya Ramachandran, Melissa Sanchez, Jenni Durieux, Sarah U. Tronnes, Joseph W. Paul, Daniel J. Esping, Samira Monshietehadi, Melissa G. Metcalf, Andrew Dillin

This study identifies a non-canonical UPRER pathway that extends lifespan through ER remodeling and lipophagy, independent of chaperone function.

bioRxiv · Nov 15, 2018 · PreprintCell Biology