Molecular BiologybioRxivPreprint
RNA decay via the nuclear exosome is essential for piwi-mediated transposon silencing
Changwei Yu, Toni Manolova, László Tirián…·Julius Brennecke
The paper shows that the Drosophila Piwi-piRNA pathway silences transposons by degrading their RNA via the nuclear exosome, with TEsup proteins facilitating this process.