Author

Kaltinaitis B. Santos

University of Massachusetts Chan Medical SchoolORCID 0000-0002-9740-9253Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1

Frequent Co-Authors

Adı́lson GuilhermeiD· 2 shared Hui WangiD· 2 shared Lawrence M. LifshitziD· 2 shared Leslie A. RowlandiD· 2 shared Michael CzechiD· 2 shared Sarah M. C. NicoloroiD· 2 shared Batuhan YenilmeziD· 1 shared Emmanouela TsagkarakiiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersPhysiology

Adı́lson GuilhermeORCID

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2 papers

Recent·Most cited

Thermogenic adipocytes alleviate hepatic steatosis and insulin resistance via macrophage cytokine secretion in obese mice

Hui Wang, Mark Kelly, Najihah Aziz, Emmanouela Tsagkaraki, Sarah M. C. Nicoloro, Lawrence M. Lifshitz, Adı́lson Guilherme, Leslie A. Rowland, Batuhan Yenilmez, Kaltinaitis B. Santos, Naideline Raymond, Tiffany DeSouza, Muhammad Tanveer Sajid, Hanna Choi, LAUREN A. TAUER, , Michael Czech

This study shows that adipocyte Nrip1 deficiency in obese mice reduces hepatic steatosis and insulin resistance by promoting M2-like macrophages that secrete IL-1rn.

bioRxiv · Aug 1, 2025 · PreprintPhysiology

The autophagy receptor Ncoa4 controls PPARγ activity and thermogenesis in brown adipose tissue

Leslie A. Rowland, Kaltinaitis B. Santos, Adı́lson Guilherme, Sean Munroe, Lawrence M. Lifshitz, Sarah M. C. Nicoloro, Hui Wang, Matthew F. Yee, Michael Czech

This study identifies Ncoa4 as a regulator of PPARγ activity and thermogenesis in brown adipose tissue through genetic and functional analyses.

bioRxiv · Feb 2, 2025 · PreprintMolecular Biology