Franz Weber

Circuit mechanism underlying fragmented sleep and memory deficits in 16p11.2 deletion mouse model of autism

This study identifies heightened LC-NE neuron activity and altered connectivity as causes of sleep fragmentation and memory deficits in a 16p11.2 deletion ASD mouse model.

A hypothalamic circuit mechanism underlying the impact of stress on memory and sleep

This study identifies a hypothalamic circuit involving CRHPVN neurons that mediates stress-induced impairments in memory and sleep.

Homeostatic regulation of REM sleep by the preoptic area of the hypothalamus

This study identifies GABAergic neurons in the hypothalamic preoptic area that regulate REM sleep homeostasis by responding to REM sleep restriction and mediating rebound.

Infralimbic activity during REM sleep facilitates fear extinction memory

This study shows that REM sleep after fear conditioning enhances infralimbic cortex excitability, which is crucial for fear extinction memory consolidation.

Regulation of stress-induced sleep fragmentation by preoptic glutamatergic neurons

This study identifies POA glutamatergic neurons as regulators of stress-induced sleep fragmentation through optogenetic manipulation and calcium activity analysis in mice.

Regulation of REM Sleep by Inhibitory Neurons in the Dorsomedial Medulla

This study shows that GABAergic neurons in the dorsomedial medulla promote REM sleep initiation and maintenance through projections to raphe nuclei and synchronization with infraslow oscillations during NREMs.