Kyuhyun Choi

Acute social defeat induces cannabinoid type 1 receptor-dependent synaptic depression in the anterior ventral subiculum to anterior hypothalamic nucleus pathway to drive social avoidance in male mice

This study identifies a CB1R-dependent synaptic depression in the avSUB->AHN pathway that drives social avoidance in male mice following acute social defeat stress.

Brain-Resident CD8+ T Cells Regulate Neuronal Activity and Behavior via Interferon-Gamma

This study identifies brain-resident CD8+ T cells that regulate neuronal activity and behavior through interferon-gamma secretion, showing their role in maintaining brain homeostasis.

Striatal interneuron microcircuits gate reinforcement to stabilize adaptive choice

This study identifies a striatal interneuron circuit that gates reinforcement by linking outcome processing to adaptive action selection through disinhibitory microcircuitry.

Histone variant H2BE controls activity-dependent gene expression and homeostatic scaling

This study shows that H2BE is required for activity-dependent gene expression and homeostatic scaling in neurons.

Temporally and Functionally Distinct Contributions to Value Based Choice Along the Anterior-Posterior Dorsomedial Striatal Axis

This study investigates how different regions of the dorsomedial striatum contribute to value-based decision-making in mice through distinct temporal coding patterns and neural activity.

Histone variant H2BE enhances chromatin accessibility in neurons to promote synaptic gene expression and long-term memory

This study identifies H2BE as a widely expressed H2B variant that enhances chromatin accessibility in neurons, promoting synaptic gene expression and long-term memory.

Infralimbic activity during REM sleep facilitates fear extinction memory

This study shows that REM sleep after fear conditioning enhances infralimbic cortex excitability, which is crucial for fear extinction memory consolidation.

Distributed processing for action control by prelimbic circuits targeting anterior-posterior dorsal striatal subregions.

The paper identifies distinct prefrontal circuits targeting anterior and posterior dorsal striatum subregions and characterizes their roles in action control during a choice task.