Ying Liu

Application of machine learning to discriminate photoreceptor cell species in xenotransplanted chimeric retinas

The paper develops a machine learning method to distinguish donor human photoreceptor cells from recipient animal cells in xenotransplanted retinas using nuclear morphology features.

Macrophage Migration Inhibitory Factor Suppresses Natural Killer Cell Response and Promotes Hypoimmunogenic Stem Cell Engraftment Following Spinal Cord Injury

This study shows that overexpressing MIF in hypoimmunogenic iPSC-derived NPCs reduces NK cell attack and improves engraftment in SCI models.

Cell-specific regulation of gene expression using splicing-dependent frameshifting.

This paper introduces SLED, a splicing-based method to control gene expression in specific cell types, demonstrating its utility in targeting neurons, photoreceptors, and cancer cells.

Transretinal migration of astrocytes and brain/spinal cord-like cells arising from transplanted human retinal organoids.

This study transplants human retinal organoids into mice and identifies two classes of graft-derived cells with distinct migration and maturation behaviors.

Quantifiable In Vivo Imaging Biomarkers of Retinal Regeneration by Photoreceptor Cell Transplantation

The paper develops a quantifiable imaging biomarker grading scheme using cSLO to track long-term changes in photoreceptor cell grafts in mice.