Author

Minzhong Yu

Cleveland ClinicORCID 0000-0002-3115-8930Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:mouse· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:benchmarking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Neal S. PeacheyiD· 3 shared Patrick J. LeaveyiD· 2 shared Seth BlackshawiD· 2 shared Alexei M. BygraveiD· 1 shared Ben LangmeadiD· 1 shared Benjamin G. Dubner· 1 shared Clayton P. SantiagoiD· 1 shared Dong Won KimiD· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersNeuroscience

Neal S. PeacheyORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cell-specific regulation of gene expression using splicing-dependent frameshifting.

Jonathan P. Ling, Alexei M. Bygrave, Clayton P. Santiago, Rogger P. Carmen‐Orozco, Vickie Trinh, Minzhong Yu, Yini Li, Ying Liu, Kyra D. Bowden, Leighton H. Duncan, Jeong Soon Han, Kamil Taneja, Rochinelle Dongmo, Travis A. Babola, Patrick Parker, , Seth Blackshaw

This paper introduces SLED, a splicing-based method to control gene expression in specific cell types, demonstrating its utility in targeting neurons, photoreceptors, and cancer cells.

Nature Communications · Oct 1, 2022Peer-reviewedMolecular Biology

Ptbp1 deletion does not induce glia-to-neuron conversion in adult mouse retina and brain.

Thanh V. Hoang, Dong Won Kim, Haley Appel, Nicole A. Pannullo, Patrick J. Leavey, Manabu Ozawa, Sika Zheng, Minzhong Yu, Neal S. Peachey, Juhyun Kim, Seth Blackshaw

This study shows that deleting Ptbp1 in adult retinal Muller glia and brain astrocytes does not convert glia into neurons, using genetic lineage tracing, scRNA-Seq, and electrophysiology.

bioRxiv · Oct 4, 2021 · PreprintNeuroscience

Microglial activation in an amyotrophic lateral sclerosis-like model caused by Ranbp2 lossand nucleocytoplasmic transport impairment in retinal ganglion neurons

Kyoungin Cho, Dosuk Yoon, Minzhong Yu, Neal S. Peachey, Paulo A. Ferreira

This paper investigates the effects of Ranbp2 loss in retinal ganglion neurons and motoneurons in an ALS-like model, revealing distinct paracrine signaling and immune responses.

Cellular and Molecular Life Sciences · Apr 3, 2019Peer-reviewedNeuroscience