Stuart J. Shankland

The paper introduces TubuleMAP, a semi-automated 3D tubule tracking pipeline for analyzing tubular networks, achieving high throughput and accuracy in reconstructing kidney and testis tubules.

This study identifies regional transcriptomic differences in mouse podocytes during injury, revealing distinct gene expression patterns and potential therapeutic targets in focal segmental glomerulosclerosis.

This study uses single-nucleus transcriptomics to analyze age-related changes in mouse kidney regions, revealing region-specific and cell-type-specific aging patterns in podocytes.

The paper develops a pipeline for high-resolution imaging and analysis of whole mouse glomeruli, revealing novel aging and disease-related phenotypes.

The paper shows that inducing DNA breaks accelerates aging-related chromatin changes and loss of cell identity in mammals.