Irene Díaz‐López

This study determines the structure of Pdcd4 bound to the 40S ribosomal subunit, revealing its binding site and mechanism in translational control.

This study examines polysomal architecture changes in a mouse model of Huntington's disease, finding compacted polysomes and increased expression of ribosome stalling relief factors.

The paper describes the structure of a human 48S initiation complex, revealing a second eIF4A helicase at the mRNA entry site that unwinds secondary structure downstream of the scanning complex.

This study shows arginine-rich CPPs like (PR)n displace DNA- and RNA-binding factors, impairing nucleic acid processes and causing toxicity, similar to PROTAMINE's effects.