Author

Sandrine Bétuing

Centre National de la Recherche ScientifiqueORCID 0000-0002-4733-6922Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Organism:human· 1

Frequent Co-Authors

Jocelyne CabocheiD· 2 shared Albert GiraltiD· 1 shared Alexis‐Pierre BemelmansiD· 1 shared Andry AndrianariveloiD· 1 shared Anna PetitboniD· 1 shared Benoit de PinsiD· 1 shared Charlène JoséphineiD· 1 shared Enejda SubashiiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersNeuroscience

Jocelyne CabocheORCID

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2 papers

Recent·Most cited

PYK2 in the dorsal striatum of Huntington disease R6/2 mouse model

Omar Al–Massadi, Mélody Labarchède, Benoit de Pins, Sophie Longueville, Albert Giralt, Théano Irinopoulou, Mythili Savariradjane, Enejda Subashi, Sílvia Ginés, Jocelyne Caboche, Louise‐Laure Mariani, Sandrine Bétuing, Jean‐Antoine Girault

This study examines PYK2 levels and effects of its restoration in the striatum of HD mouse models and human patients, finding reduced levels but only partial improvement in motor phenotypes.

Neurobiology of Disease · Feb 17, 2025Peer-reviewedNeuroscience

Disrupting D2-NMDA receptor heteromerization blocks the rewarding effects of cocaine but preserves natural reward processing

Andry Andrianarivelo, Estefani Saint‐Jour, Paula A. Pousinha, Sebastián P. Fernández, Anna Petitbon, Véronique De Smedt, Nicolas Heck, Vanesa Ortiz, Marie‐Charlotte Allichon, Vincent Kappès, Sandrine Bétuing, Roman Walle, Ying Zhu, Charlène Joséphine, Alexis‐Pierre Bemelmans, , Peter Vanhoutte

The paper shows disrupting D2-NMDA receptor heteromerization blocks cocaine's rewarding effects without affecting natural reward processing in mice and humans.

bioRxiv · Jan 25, 2021 · PreprintNeuroscience