Author
Biomedical Research Networking Center on Neurodegenerative DiseasesORCID 0000-0002-9479-8185Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Omar Al–Massadi, Mélody Labarchède, Benoit de Pins…·Jean‐Antoine Girault
This study examines PYK2 levels and effects of its restoration in the striatum of HD mouse models and human patients, finding reduced levels but only partial improvement in motor phenotypes.
Arnaldo Parra‐Damas, Anna del Ser‐Badia, Xavier Fernandez-Olalla…·Carlos A. Saura
The paper identifies CREB/CRTC1-regulated gene programs that link synaptic activity to transcriptional control of NMDA receptor-mediated plasticity and memory in hippocampal neurons.
Anika Pupak, Irene Rodríguez-Navarro, Kirupa Sathasivam…·Verónica Brito
This study investigates how m6A RNA modifications in Htt intron 1 regulate the production of the pathogenic Htt1a transcript in Huntington's Disease.
Verónica Brito, Enrica Montalban, Anna Sancho‐Balsells…·Albert Giralt
The paper shows that Egr1-dependent hippocampal neuronal ensembles limit motor learning in mice.
Núria Martín‐Flores, Leticia Pérez‐Sisqués, Jordi Creus‐Muncunill…·Cristina Malagelada
This study shows that RTP801 mediates motor learning dysfunction in Huntington's disease by affecting synaptic plasticity, suggesting a therapeutic target through the RTP801/Akt/mTOR pathway.
David Moreno‐Delgado, Mar Puigdellívol, Estefanía Moreno…·Peter James McCormick
This study identifies D1R-H3R heteromers as a therapeutic target for Huntington’s disease by showing their role in dopamine signaling and their modulation by H3R antagonists.