ERIC D. ADLER

A Translational Model of MASLD-Associated HFpEF Defines Mitochondrial Dysfunction and Cardiac Plasticity During Disease Progression and Regression

This paper develops a mouse model of MASLD-associated HFpEF, showing mitochondrial dysfunction and cardiac plasticity, and demonstrates reversibility with dietary intervention.

Lipoxins Regulate Intercalated Disk-Associated Signaling and Immune Remodeling in Dilated Cardiomyopathy

This study shows lipoxins modulate immune responses and cardiac signaling in male MLPko mice with dilated cardiomyopathy, but not in females.

Human iPSC gene signatures and X chromosome dosage impact response to WNT inhibition and cardiac differentiation fate

The paper investigates how non-genetic variability in iPSC lines affects their response to WNT inhibition and cardiac differentiation, identifying 91 signature genes and X chromosome dosage differences as key factors.