Author

Mengwei Yang

Boston UniversityORCID 0000-0002-4775-5406Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Gustavo MostoslavskyiD· 2 shared Aldana D. GojanovichiD· 1 shared Andrés A. Quiñones-MolinaiD· 1 shared Andrew J. HendersoniD· 1 shared Anna C. BelkinaiD· 1 shared Charles M. KerriD· 1 shared Dar M. HeinzeiD· 1 shared Feiya WangiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

Gustavo MostoslavskyORCID

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2 papers

Recent·Most cited

Generation of effector CD4+ T cells from Human iPSC

Julian Amirault, Dar M. Heinze, Mengwei Yang, Charles M. Kerr, Pushpinder Bawa, Laura Polanco, Gabriel Sgambettera, Feiya Wang, Anna C. Belkina, Jennifer E Snyder-Cappione, Gustavo Mostoslavsky

This paper generates functional CD4+ T cells from human iPSC by modulating Notch signaling, showing cytokine diversity and transcriptional similarity to blood CD4+ T cells.

Stem Cell Reports · Aug 27, 2026Peer-reviewedImmunology

Expression of Intron-containing HIV-1 RNA Induces NLRP1 Inflammasome Activation in Myeloid Cells

Sallieu Jalloh, I A Hughes, Hisashi Akiyama, Aldana D. Gojanovich, Andrés A. Quiñones-Molina, Mengwei Yang, Andrew J. Henderson, Gustavo Mostoslavsky, Suryaram Gummuluru

This study shows that HIV-1 intron-containing RNA induces NLRP1 inflammasome activation and IL-1β secretion in myeloid cells through a RLR- and endosomal TLR-independent mechanism.

PLoS Biology · Sep 8, 2025Peer-reviewedMicrobiology