Author

In‐Young Hwang

Institute for Basic ScienceORCID 0000-0002-4633-3658Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Changjoon Justin LeeiD· 2 shared Boyoung LeeiD· 1 shared Doo‐Wan ChoiD· 1 shared Heeyoung AniD· 1 shared Henrik M. HammaréniD· 1 shared Hoon RyuiD· 1 shared Hye Yeong LeeiD· 1 shared Hye-Lan LeeiD· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersNeuroscience

Changjoon Justin LeeORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

TRANsCre-DIONE transdifferentiates scar-forming reactive astrocytes into functional motor neurons

Heeyoung An, Hye-Lan Lee, Doo‐Wan Cho, Jinpyo Hong, Hye Yeong Lee, Jung Moo Lee, SunYeong Choi, In‐Young Hwang, Junsung Woo, Jaekwang Lee, Mingu Park, Young‐Su Yang, Su-Cheol Han, Yoon Ha, Changjoon Justin Lee

This paper describes a method to convert reactive astrocytes into functional motor neurons with high efficiency and specificity using TRANsCre-DIONE, leading to improved motor recovery in spinal cord injury.

Experimental & Molecular Medicine · Sep 11, 2026Peer-reviewedNeuroscience

Hyperactivation of the AXL-ICD/SIRT2 axis by Amyloid-β impairs astrocytic autophagic flux and exacerbates neuroinflammation

Tai Young Kim, Mridula Bhalla, Uiyeol Park, Seung Jae Hyeon, In‐Young Hwang, Youngsuk Seo, Wongu Youn, Jin-A Lee, Jung-Hee Lee, Boyoung Lee, Hoon Ryu, Changjoon Justin Lee

This study identifies the AXL-ICD/SIRT2 axis as a mechanism by which amyloid-β impairs astrocytic autophagy and exacerbates neuroinflammation in Alzheimer's disease.

bioRxiv · Aug 31, 2026 · PreprintNeuroscience

Comparative chromatin accessibility upon BDNF-induced neuronal activity delineates neuronal regulatory elements

Ignacio L. Ibarra, Vikram Singh Ratnu, Lucia Gordillo, In‐Young Hwang, Luca Mariani, Kathryn Weinand, Henrik M. Hammarén, Martha L. Bulyk, Mikhail M. Savitski, Judith B. Zaugg, Kyung‐Min Noh

The paper identifies BDNF-specific chromatin accessibility changes in neurons and links them to gene regulation and neurodevelopmental traits.

bioRxiv · May 28, 2021 · PreprintGenomics