Author

Zainab Harissa

Washington University in St. LouisORCID 0000-0003-4712-1814Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Amanda R. DicksiD· 2 shared Farshid GuilakiD· 2 shared Nancy S. Steward· 2 shared Aat A. MulderiD· 1 shared Alireza SavadipouriD· 1 shared Berend B.R. de Koning· 1 shared Chia‐Lung WuiD· 1 shared Colin G. NicholsiD· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersDevelopmental Biology

Amanda R. DicksORCID

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2 papers

Recent·Most cited

Developmental BiologyeLifePeer-reviewedFeb 13, 2023

Skeletal dysplasia-causing TRPV4 mutations suppress the hypertrophic differentiation of human iPSC-derived chondrocytes

Amanda R. Dicks, Grigory I. Maksaev, Zainab Harissa…·Farshid Guilak

This study investigates how TRPV4 mutations affect chondrocyte differentiation and identifies altered BMP signaling as a mechanism for skeletal dysplasia.

26 citationstop 3%

humanbulk RNA-seq

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Molecular BiologybioRxivPreprintDec 19, 2022

A high-impact COL6A3 mutation alters the response of chondrocytes in neo-cartilage organoids to hyper-physiologic mechanical loading

Niek G.C. Bloks, Zainab Harissa, Shaunak Sanjay Adkar…·Ingrid Meulenbelt

This paper investigates how a COL6A3 mutation affects chondrocyte response to mechanical stress in a human iPSC-derived cartilage organoid model, finding reduced PCM protein binding and impaired stress response.

2 citations

humanexperimental assay

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