Alan Tracey

This study uses CRISPR-Cas9 to induce deletions in the SULT-OR gene of Schistosoma mansoni, showing potential for oxamniquine resistance but limited mRNA knockdown due to low mutation frequency.

The paper identifies a single major QTL on chromosome V associated with ivermectin resistance in Haemonchus contortus through genome-wide analysis of genetic crosses.

The paper reports the discovery of a new bacterial species, Candidatus Ornithobacterium hominis, identified from nasopharyngeal swabs and describes its genomic features and colonization patterns.

This paper demonstrates CRISPR/Cas9-based genome editing in Schistosoma mansoni, successfully mutating the omega-1 gene and reducing Th2 cytokine responses and granuloma formation.

The paper characterizes a hybrid schistosome in Europe, revealing its genomic composition and compatibility with hosts, and improves the genome assembly of its parental species.

This paper compares genomes of 81 nematode and platyhelminth species to identify gene families related to parasitism and prioritize new drug targets.

This paper constructs a genetic map of Haemonchus contortus using whole-genome resequencing, revealing recombination patterns and reproductive traits like polyandry and polyploidy.

The paper compares the transcriptome of Haemonchus contortus parasites from vaccinated and control sheep to assess vaccine-induced gene expression changes.

The paper compares bacterial genome assembly software for MinION data, finding Canu provides the most accurate assembly while Miniasm is fastest.