Author

Michael I. Rauchman

Washington University in St. LouisORCID 0000-0002-4820-3689Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Jeannine M. BastaiD· 2 shared Lisa Stout· 2 shared Lynn RobbinsiD· 2 shared Michelle BrennaniD· 2 shared Aditya SurapaneniiD· 1 shared Agnes B. FogoiD· 1 shared Amanda L. KnoteniD· 1 shared Ana Catherine RicardoiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersMolecular Biology

Jeannine M. BastaORCID

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Author profile →

3 papers

Recent·Most cited

Cellular and Spatial Drivers of Unresolved Injury and Functional Decline in the Human Kidney

Blue B. Lake, Ricardo Melo Ferreira, Jens Hansen, Rajasree Menon, Jeannine M. Basta, Heather Thiessen‐Philbrook, Stephanie Reinert, Robin Fallegger, Asmita Kishor Lagwankar, Xi Chen, Soumya Maity, Katerina V. Djambazova, Brittney L. Gorman, Nicholas Lucarelli, Debora L. Gisch, , Sanjay R. Jain

The paper presents a multi-modal atlas of human kidney disease, identifying cellular and spatial mechanisms of injury resolution or failure and linking them to clinical outcomes.

bioRxiv · Sep 26, 2025 · PreprintMolecular Biology

Deletion of NuRD component Mta2 in nephron progenitor cells causes developmentally programmed FSGS

Jeannine M. Basta, Lynn Robbins, Lisa Stout, Michelle Brennan, John P. Shapiro, Mary Chen, Darcy R. Denner, Ángel Baldán, Nidia Cordeiro Messias, Sethu M. Madhavan, Samir V. Parikh, Michael I. Rauchman

This study shows that deleting Mta2 in nephron progenitor cells leads to low nephron number, which causes FSGS and CKD through impaired mitochondrial lipid metabolism and gene regulation.

bioRxiv · Oct 18, 2023 · PreprintDevelopmental Biology

Analysis of FGF20-regulated genes in organ of Corti progenitors by translating ribosome affinity purification

Lu M. Yang, Lisa Stout, Michael I. Rauchman, David M. Ornitz

The paper uses TRAPseq to identify FGF20-regulated genes in mouse organ of Corti progenitors, finding genes involved in hair cell differentiation and hearing loss.

Developmental Dynamics · Jun 3, 2020Peer-reviewedDevelopmental Biology