Author

Appaso Mahadev Jadhav

Scripps Research InstituteORCID 0000-0002-4892-0792Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Assay:proteomics· 1

Frequent Co-Authors

Alireza Rahimi· 1 shared Amal Gebara-LambiD· 1 shared Anil K. Sen GuptaiD· 1 shared Anil VasudevaniD· 1 shared Anshul Chaudhary· 1 shared Anurupa Shrestha· 1 shared Arnab K. ChatterjeeiD· 1 shared Ashley K. Woods· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperPharmacology & Toxicology

Alireza Rahimi

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Pan-Coronavirus Protease Engagement and Differentiated Pharmacology of Antiviral Candidate CMX990

N. G. R. Dayan Elshan, Karen C. Wolff, Laura Riva, Malina A. Bakowski, Simeon Babarinde, Anshul Chaudhary, Mark Zeller, Ashley K. Woods, Gennadii A. Grabovyi, Katy B. Wilson, Rebecca A. Leonard, Briana Lynn McGovern, Jared Benjamin, Isidora D. Suazo, Mary Gordon, , Arnab K. Chatterjee

This study evaluates CMX990, a coronavirus Mpro inhibitor, showing broad antiviral activity against multiple coronaviruses and superior pharmacologic properties compared to existing inhibitors.

bioRxiv · Oct 1, 2026 · PreprintPharmacology & Toxicology

Proteome-Wide Discovery of Degradable Proteins Using Bifunctional Molecules

Ines Forrest, Louis Patrick Conway, Clara Gathmann, Appaso Mahadev Jadhav, Tzu-Yuan Chiu, Christian M. Chaheine, Michelle A. Estrada, Anurupa Shrestha, Kathy Sarris, Justin M. Reitsma, Scott E. Warder, Anil Vasudevan, Shaun M. McLoughlin, Christopher G. Parker

The paper introduces AgnoTACs, bifunctional molecules that enable proteome-wide discovery of degradable proteins, identifying over 50 previously untargeted proteins.

ACS Central Science · Oct 21, 2025Peer-reviewedBiochemistry