Author

Michelle A. Estrada

AbbVie (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

Shaun M. McLoughlin· 2 shared Aaron C. EhlingeriD· 1 shared Anil VasudevaniD· 1 shared Anurupa Shrestha· 1 shared Appaso Mahadev JadhaviD· 1 shared Christian M. ChaheineiD· 1 shared Christopher G. ParkeriD· 1 shared Clara GathmanniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBiochemistry

Shaun M. McLoughlin

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Author profile →

2 papers

Recent·Most cited

Native Mass Spectrometry Reveals Distinct Effects of Linker Length and Targeting-Ligand Identity on PROTAC Ternary Complexes

Evan N. Whitford, Joshua D. Gilbert, Marius M. Kostelic, Michelle A. Estrada, Aaron C. Ehlinger, Tiffany A. Thibaudeau, Shaun M. McLoughlin, Vicki Hopper Wysocki

This study uses native mass spectrometry to show how PROTAC linker length and targeting ligand affect ternary complex structure and stability.

bioRxiv · Sep 30, 2026 · PreprintBiochemistry

Proteome-Wide Discovery of Degradable Proteins Using Bifunctional Molecules

Ines Forrest, Louis Patrick Conway, Clara Gathmann, Appaso Mahadev Jadhav, Tzu-Yuan Chiu, Christian M. Chaheine, Michelle A. Estrada, Anurupa Shrestha, Kathy Sarris, Justin M. Reitsma, Scott E. Warder, Anil Vasudevan, Shaun M. McLoughlin, Christopher G. Parker

The paper introduces AgnoTACs, bifunctional molecules that enable proteome-wide discovery of degradable proteins, identifying over 50 previously untargeted proteins.

ACS Central Science · Oct 21, 2025Peer-reviewedBiochemistry