Author

Tzu-Yuan Chiu

Scripps Research InstituteORCID 0000-0001-8702-9268Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 3 Research Focus:drug response / drug discovery· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1

Frequent Co-Authors

Christopher G. ParkeriD· 3 shared Clara GathmanniD· 2 shared Stefano ForliiD· 2 shared Andrew B. WardiD· 1 shared Anil VasudevaniD· 1 shared Anurupa Shrestha· 1 shared Appaso M. Jadhav· 1 shared Appaso Mahadev JadhaviD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBiochemistry

Christopher G. ParkerORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The SLC15A4-LAMTOR1 interaction licenses endolysosomal TLR-mediated mTOR signaling and inflammatory cytokine production

Tzu-Yuan Chiu, Peter-Rory Hall, Daniel C. Lazar, Arthur Kim, Stefano Forli, Andrew B. Ward, John Ross Teijaro, Christopher G. Parker

This paper identifies a direct interaction between SLC15A4 and LAMTOR1 that is required for endolysosomal TLR-mediated mTOR signaling and inflammatory cytokine production.

bioRxiv · Jun 9, 2026 · PreprintImmunology

Post-Translational Modifications Remodel Proteome-Wide Ligandability

Weichao Li, Qijia Wei, Manuel A. Llanos, Clara Gathmann, Paolo Governa, Tzu-Yuan Chiu, Jacob M. Wozniak, Appaso M. Jadhav, Matthew Holcomb, Jacob B. Cravatt, Ashok R. Dongré, Mia L. Huang, Stefano Forli, Christopher G. Parker

The paper identifies how post-translational modifications affect protein ligandability by profiling PTM-dependent small-molecule interactions in human cells.

Nature Chemical Biology · May 5, 2026Peer-reviewedBiochemistry

Proteome-Wide Discovery of Degradable Proteins Using Bifunctional Molecules

Ines Forrest, Louis Patrick Conway, Clara Gathmann, Appaso Mahadev Jadhav, Tzu-Yuan Chiu, Christian M. Chaheine, Michelle A. Estrada, Anurupa Shrestha, Kathy Sarris, Justin M. Reitsma, Scott E. Warder, Anil Vasudevan, Shaun M. McLoughlin, Christopher G. Parker

The paper introduces AgnoTACs, bifunctional molecules that enable proteome-wide discovery of degradable proteins, identifying over 50 previously untargeted proteins.

ACS Central Science · Oct 21, 2025Peer-reviewedBiochemistry