Soraya Martín‐Suárez

Traumatic brain injury modifies adult hippocampal neural stem cell fate to promote neurogenesis at the cost of astrogliogenesis.

This study shows that traumatic brain injury shifts adult hippocampal neural stem cell fate toward neurogenesis and away from astrogliogenesis, using single-cell RNA sequencing and spatial transcriptomics.

Hippocampal reactive neural stem cells are able to phagocytose and have an immunological molecular signature

The paper identifies hippocampal reactive neural stem cells (react-NSCs) as phagocytic and immunologically active cells in two pathological models, MTLE and TBI.

Generation of adult hippocampal neural stem cells occurs in the early postnatal dentate gyrus and depends on cyclin D2

This study shows that adult hippocampal neural stem cells (aNSCs) form in the early postnatal dentate gyrus and require cyclin D2 for their development.

HB-EGF and zinc activate EGFR to induce reactive neural stem cells in the mouse hippocampus after seizures

The paper shows that seizures in mice disrupt the hippocampal neurogenic niche by inducing reactive neural stem cells via the EGFR pathway, and inhibiting EGFR improves neurogenesis.

Acute inhibition of the STA3 signaling pathway during epileptogenesis prevent GABAergic cells loss and imprinting of epileptic state: an in-vitro proof

This study shows that inhibiting STAT3 signaling during epileptogenesis prevents epileptic activity, cell loss, and inflammatory glial states in an in vitro model.