Author

Bryony L. Winters

The University of SydneyORCID 0000-0002-4973-0771Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Assay:electronic health records· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1 Organism:rat· 1

Frequent Co-Authors

Brent Vander WykiD· 1 shared Carina L. BlakeriD· 1 shared Charlie W Gregson· 1 shared Elena E. BagleyiD· 1 shared Elizabeth ClarkeiD· 1 shared Gabrielle C. GregoriouiD· 1 shared Heather Gwynn AlloreiD· 1 shared John MachiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperPharmacology & Toxicology

Brent Vander WykORCID

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2 papers

Recent·Most cited

Effect of prescribing and deprescribing oxycodone on pain and function in a mouse model of osteoarthritis: impact of polypharmacy and sex on response

John Mach, Carina L. Blaker, Bryony L. Winters, Yo Otsu, Elizabeth Clarke, Heather Gwynn Allore, Brent Vander Wyk, Kevin Winardi, Roderick Peel, Charlie W Gregson, Neda Assareh, Michelle Kourieh, Sarah Nicole Hilmer

This study evaluates the effects of oxycodone prescribing and deprescribing in a mouse model of osteoarthritis, showing that polypharmacy worsens outcomes and sex differences exist in treatment response.

bioRxiv · Oct 22, 2025 · PreprintPharmacology & Toxicology

Opioid withdrawal abruptly disrupts amygdala circuit function by reducing peptide actions

Gabrielle C. Gregoriou, Sahil Patel, Sebastian Pyne, Bryony L. Winters, Elena E. Bagley

The paper shows opioid withdrawal reduces peptide activity in the amygdala by increasing neprilysin via PKA, disrupting synaptic transmission and potentially leading to compulsive drug use.

Journal of Neuroscience · Feb 13, 2023Peer-reviewedNeuroscience