Stuart Greenhill

This paper introduces nanoporous microelectrodes for in situ electrophysiological recordings in organotypic brain slices, demonstrating their viability for three weeks of culture.

This study shows CBD enhances GABAAR-mediated inhibition only after status epilepticus in rats and human tissue, suggesting it acts as a positive allosteric modulator at GABAARs.

This paper presents a wireless EEG telemeter with integrated optogenetic stimulation for long-term recording in freely-moving rats, enabling manipulation of cortical oscillations.

This study investigates how CBD modulates LPI-GPR55 signaling at excitatory and inhibitory synapses, showing its role in reducing seizure activity by blocking LPI's pro-excitatory effects and enhancing inhibitory synaptic strength.

The paper demonstrates that patient-derived monoclonal GABAA receptor antibodies cause catatonia and seizures in rodents, providing a model for autoimmune encephalitis and supporting antibody depletion as a treatment.

This study develops an NMDAR-Ab-mediated rat seizure model and shows that reducing excitatory neurotransmission, not inhibitory, causes seizures, which can be mitigated by a neurosteroid.