Laura E. Crotty Alexander

This study shows that e-cigarette vaping increases adenoma formation in a mouse model of colorectal cancer, with dual exposure to e-cigarettes and cigarettes leading to greater tumorigenesis.

The paper profiles the active cistrome in peripheral leukocytes of critically ill COVID-19 patients to identify severity-associated cis-regulatory elements and their regulatory programs.

The paper identifies a conserved 166-gene host immune signature across viral pandemics, with a 20-gene subset predicting disease severity and guiding therapeutic strategies.

This study shows that cigarette smoke and e-cigarette vapor reduce WWOX expression in lungs, leading to increased ARDS severity in mice.