Author

Natalie Vaninov

Icahn School of Medicine at Mount SinaiORCID 0000-0002-5133-6941Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Approach:deep learning· 1 Assay:flow cytometry· 1

Frequent Co-Authors

Aparna AnanthanarayananiD· 2 shared Cansu Cimen BozkusiD· 2 shared Guillaume MestralletiD· 2 shared Matthew BrowniD· 2 shared Nicolas VabretiD· 2 shared Nina BhardwajiD· 2 shared Robert M. SamsteiniD· 2 shared Aimee L. Lucas· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersImmunology

Aparna AnanthanarayananORCID

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2 papers

Recent·Most cited

Coordinated macrophage and T cell interactions mediate response to checkpoint blockade in colorectal cancer.

Guillaume Mestrallet, Matthew Brown, Natalie Vaninov, Nam Woo Cho, Leandra G. Velazquez, Aparna Ananthanarayanan, Matthew H. Spitzer, Nicolas Vabret, Cansu Cimen Bozkus, Robert M. Samstein, Nina Bhardwaj

This study identifies T cell and macrophage subsets that mediate response to anti-PD-1 therapy in colorectal cancer, showing that combination therapy can eradicate tumors in both MMRd and MMRp settings.

Cell Reports Medicine · May 1, 2026Peer-reviewedImmunology

Targeting neoantigens conserved across organs and species overcomes tumor immune escape

Guillaume Mestrallet, Ross W. Ward, Matthew Brown, Jesse Boumelha, Frederika Rentzeperis, Natalie Vaninov, Miriam Saffern, Ezekiel Olumuyide, Prerna Suri, Sreekumar Balan, Leandra Velazquez, Aparna Ananthanarayanan, Zhihong Chen, Aimee L. Lucas, Miriam Mérad, , Nina Bhardwaj

This study identifies conserved neoantigens across species and tissues that elicit strong immune responses and suppress tumor growth through vaccination.

bioRxiv · Sep 25, 2025 · PreprintImmunology