Author

Sreekumar Balan

Tisch Cancer InstituteORCID 0000-0002-2092-5145Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Assay:CITE-seq· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Aparna AnanthanarayananiD· 2 shared Nina BhardwajiD· 2 shared Adam M. FarkasiD· 1 shared Aimee L. Lucas· 1 shared Amir HorowitziD· 1 shared Ante PerosiD· 1 shared Cansu Cimen BozkusiD· 1 shared Dina YoussefiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersImmunology

Aparna AnanthanarayananORCID

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2 papers

Recent·Most cited

Targeting neoantigens conserved across organs and species overcomes tumor immune escape

Guillaume Mestrallet, Ross W. Ward, Matthew Brown, Jesse Boumelha, Frederika Rentzeperis, Natalie Vaninov, Miriam Saffern, Ezekiel Olumuyide, Prerna Suri, Sreekumar Balan, Leandra Velazquez, Aparna Ananthanarayanan, Zhihong Chen, Aimee L. Lucas, Miriam Mérad, , Nina Bhardwaj

This study identifies conserved neoantigens across species and tissues that elicit strong immune responses and suppress tumor growth through vaccination.

bioRxiv · Sep 25, 2025 · PreprintImmunology

Natural Killer Cell Dysfunction In Human Bladder Cancer Is Caused By Tissue-Specific Suppression of SLAMF6 Signaling

Adam M. Farkas, Dina Youssef, Michelle A. Tran, Sreekumar Balan, Jenna H. Newman, François Audenet, Harry Anastos, Leandra G. Velazquez, Ante Peros, Aparna Ananthanarayanan, Jorge Daza, Elena González-Gugel, Keerthi Caroline Sadanala, Jakob Theorell, Matthew D. Galsky, , Nina Bhardwaj

This study identifies SLAMF6 signaling suppression in bladder cancer tumor microenvironment as a cause of NK cell dysfunction, showing restoration of function under normoxic conditions.

bioRxiv · Apr 30, 2024 · PreprintImmunology