This study finds that adult brain age is more influenced by early life factors like birth weight and polygenic scores than by longitudinal brain decline.

eLife · Nov 10, 2021Peer-reviewedNeuroscience

Education and income show heterogeneous relationships to lifespan brain and cognitive differences across European and US cohorts

Kristine Beate Walhovd, Anders M. Fjell, Yunpeng Wang, Inge K. Amlien, Athanasia M. Mowinckel, Ulman Lindenberger, Sandra Düzel, David Bartrés-faz A, Klaus P. Ebmeier, Christian Andre Drevon, William F.C. Baaré, Paolo Ghisletta, Louise Baruël Johansen, Rogier Kievit, Richard N. Henson, , Andreas M. Brandmaier

The paper examines how education and income relate to brain and cognitive differences across European and US cohorts, finding heterogeneous effects and stronger associations in US samples.

Cerebral Cortex · Jul 2, 2021Peer-reviewedNeuroscience

Integrating large-scale neuroimaging research datasets: harmonisation of white matter hyperintensity measurements across Whitehall and UK Biobank datasets

Valentina Bordin, Ilaria Bertani, Irene Mattioli, Vaanathi Sundaresan, Paul McCarthy, Sana Suri, Enikő Zsoldos, Nicola Filippini, Abda Mahmood, Luca Melazzini, Maria Marcella Laganà, Giovanna Zamboni, Archana Singh‐Manoux, Mika Kivimaki B, Klaus P. Ebmeier, , Ludovica Griffanti

This paper harmonises white matter hyperintensity measurements across two neuroimaging datasets by standardising preprocessing and modelling demographic and physiological differences.

NeuroImage · May 19, 2021Peer-reviewedNeuroscience

Individual variation in brain structural-cognition relationships in aging

Raihaan Patel, Clare E. Mackay, Michelle G. Jansen, Gabriel A. Devenyi, M Clare O'Donoghue, Mika Kivimaki B, Archana Singh‐Manoux, Enikő Zsoldos, Klaus P. Ebmeier, M. Mallar Chakravarty, Sana Suri

This paper identifies two latent brain structure-cognition associations in aging using longitudinal data from the Whitehall II Study, showing how structural variations predict cognitive decline and maintenance.

bioRxiv · Feb 19, 2021 · PreprintNeuroscience

Multimodal brain-age prediction and cardiovascular risk: The Whitehall II MRI sub-study

Ann‐Marie G. de Lange, Melis Anatürk, Sana Suri, Tobias Kaufmann, James Howard Cole, Ludovica Griffanti, Enikő Zsoldos, Daria E. A. Jensen, Nicola Filippini, Archana Singh‐Manoux, Mika Kivimaki B, Lars Tjelta Westlye, Klaus P. Ebmeier

The paper predicts brain age using multimodal MRI data from the Whitehall II cohort and links brain aging to cardiovascular risk factors.

NeuroImage · Aug 21, 2020Peer-reviewedNeuroscience

History of childbirths relates to region-specific brain aging patterns in middle and older-aged women

Ann‐Marie G. de Lange, Cláudia Barth, Tobias Kaufmann, Melis Anatürk, Sana Suri, Klaus P. Ebmeier, Lars Tjelta Westlye

This study links a history of childbirths to region-specific brain aging patterns in middle and older-aged women using brain-age prediction methods.

bioRxiv · May 8, 2020 · PreprintNeuroscience

Self-reported sleep problems are related to cortical thinning in aging but not memory decline and amyloid-β accumulation - results from the Lifebrain consortium

Anders M. Fjell, Øystein Sørensen, Inge K. Amlien, David Bartrés-faz A, Andreas M. Brandmaier, Nikolaus Buchmann, Ilja Demuth, Christian Andre Drevon, Sandra Düzel, Klaus P. Ebmeier, Paolo Ghisletta, Ane‐Victoria Idland, Tim Christian Kietzmann, Rogier Kievit, Simone Kühn, , Alzheimer’s Disease Neuroimaging Initiative

The paper examines the relationship between self-reported sleep parameters and cortical thinning in aging, finding associations with specific brain regions but not with memory decline or amyloid-β accumulation.

bioRxiv · Apr 28, 2020 · PreprintNeuroscience

Mid-life and late life activities and their relationship with MRI measures of brain structure and functional connectivity in the UK Biobank cohort

Melis Anatürk, Sana Suri, Stephen M. Smith, Klaus P. Ebmeier, Claire E. Sexton

This study examines the relationship between mid-life and late life leisure activities and MRI measures of brain structure and functional connectivity in older adults from the UK Biobank.

bioRxiv · Apr 10, 2020 · PreprintNeuroscience

Self-reported sleep relates to hippocampal atrophy across the adult lifespan - results from the Lifebrain consortium

Anders M. Fjell, Øystein Sørensen, Inge K. Amlien, David Bartrés-faz A, Dídac Macià, Nikolaus Buchmann, Ilja Demuth, Christian Andre Drevon, Sandra Düzel, Klaus P. Ebmeier, Ane‐Victoria Idland, Tim Christian Kietzmann, Rogier Kievit, Simone Kühn, Ulman Lindenberger, , Kristine Beate Walhovd

The paper examines how self-reported sleep relates to hippocampal atrophy across adulthood using data from the Lifebrain consortium and UK Biobank, finding that worse sleep is linked to faster hippocampal volume loss over time.

SLEEP · Nov 18, 2019Peer-reviewedNeuroscience