Author

Ahmed Shaaban

University of CopenhagenORCID 0000-0002-5145-3857Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Cordelia ImigiD· 2 shared Adam Davison· 1 shared Benjamin H. CooperiD· 1 shared Christiane Harenberg· 1 shared Christopher A. Smith· 1 shared Constanza AlcainoiD· 1 shared Damien J. KeatingiD· 1 shared Emily L. MiedzybrodzkaiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

Cordelia ImigORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Mechanisms of Activation and Serotonin release from Human Enterochromaffin Cells

Constanza Alcaino, Nunzio Guccio, Emily L. Miedzybrodzka, Jaden R Quale, Tianyi Lu, Adam Davison, Christopher A. Smith, Emily Overington, Marta Santos-Hernández, Mae Tabbada, Megan Hodge, Rula Bany Bakar, Richard G. Kay, Ahmed Shaaban, Cordelia Imig, , Fiona Mary Gribble

This study investigates mechanisms of serotonin release from human enterochromaffin cells using organoids and functional assays, identifying key receptors and signaling pathways involved.

Cellular and Molecular Gastroenterology and Hepatology · Jan 1, 2025Peer-reviewedCell Biology

Dissecting Functional, Structural, and Molecular Requirements for Serotonin Release from Mouse Enterochromaffin Cells

Ahmed Shaaban, Frederike Maaß, Valentin Schwarze, Mari Lilith Lund, Sabine Beuermann, Michelle Chan, Christiane Harenberg, Gavin A. Bewick, Damien J. Keating, Fritz Benseler, Benjamin H. Cooper, Cordelia Imig

The paper investigates serotonin release mechanisms from mouse enterochromaffin cells using multiple techniques and finds that serotonin is primarily released from large dense-core vesicles with slow kinetics, similar to other endocrine cells.

bioRxiv · May 28, 2021 · PreprintNeuroscience