Author

Chandrashekhar Charavaryamath

Iowa State UniversityORCID 0000-0002-5217-1608Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Alan Patrick RobertsoniD· 1 shared Alejandro Ramírez· 1 shared Andy Y. Law· 1 shared Anumantha G. KanthasamyiD· 1 shared Brett Sponseller· 1 shared Britt NibberingiD· 1 shared Céline HarmanusiD· 1 shared Colleen K. ArdisiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperPharmacology & Toxicology

Alan Patrick RobertsonORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Characterization of the clade 4 non-toxigenic C. difficile isolate L-NTCD03 carrying the cfr(B) gene

Britt Nibbering, Sam Nooij, Céline Harmanus, Ingrid M. J. G. Sanders, Inez M. Miedema, Quinten R. Ducarmon, Rolf H. A. M. Vossen, Susan L. Kloet, Colleen K. Ardis, Robert A. Britton, Farnaz Yousefi, Jenna E. Bayne, Chandrashekhar Charavaryamath, Andy Y. Law, Morgan L. Murphy, , Wiep Klaas Smits

The paper characterizes a non-toxigenic C. difficile strain, L-NTCD03, showing antimicrobial resistance and non-toxicity, suggesting its potential as a live biotherapeutic.

FEMS Microbes · Jan 1, 2026Peer-reviewedMicrobiology

Exploring the Role of Kv1.3 and MAPK14 in Mediating Microglial Oxidative Stress and Neuroinflammation Following Organic Dust Exposure

Nyzil Massey, Sanjana Mahadev Bhat, Denusha Shrestha, Emir Malovic, Locke A. Karriker, Shivani Choudhary, Alan Patrick Robertson, Hai Minh Nguyen, Heike Wulff, Anumantha G. Kanthasamy, Chandrashekhar Charavaryamath

This study investigates how Kv1.3 and MAPK14 contribute to microglial oxidative stress and neuroinflammation after organic dust exposure, finding that inhibiting Kv1.3 reduces inflammation and oxidative stress markers.

bioRxiv · Jan 10, 2025 · PreprintPharmacology & Toxicology