Mehdi Eshraghi

This study shows that autophagy and cholesterol metabolism are remodeled in glioma progression and TMZ resistance, with impaired autophagy linked to reduced cholesterol synthesis and altered lipid profiles.

This study identifies BCL2L13 as a regulator of autophagy and ceramide metabolism in glioblastoma, showing distinct effects on metabolic pathways in TMZ-resistant and sensitive cells.

This study identifies Rhes as a striatal-enriched protein that promotes mitophagy via Nix, contributing to striatal vulnerability in the brain.

This study shows mutant huntingtin (mHtt) stalls ribosomes and suppresses protein synthesis independently of FMRP, using ribosome profiling in HD cells and mouse models.