Immunomodulatory RIG-I Agonist SLR14 Confers Protection Against a Range of Highly Pathogenic Negative Sense RNA viruses
Kristina Meier, Judith Olejnik, Joseline Velasquez-Reyes, Jonna B. Westover, Pushpinder Bawa, Elizabeth R. Wrobel, Corey W. Henderson, Pan Hu, Adam J. Hume, Alexander M. Holtz, Olga Fedorova, Gustavo Mostoslavsky, Darrell N. Kotton, John H. Connor, Andrea Marzi, , Elke Mühlberger
SLR14, an immunomodulatory RIG-I agonist, provides broad-spectrum antiviral protection against multiple highly pathogenic negative-sense RNA viruses in vitro and in vivo.
bioRxiv · Oct 10, 2026 · PreprintMicrobiology