Author

Regan N. Szalay

Harvard UniversityORCID 0000-0002-5438-1596Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:CRISPR screen· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Assay:proteomics· 1 Research Focus:software / tool· 1

Frequent Co-Authors

J. Keith JoungiD· 2 shared Julian GrünewaldiD· 2 shared Andrew E. H. EliaiD· 1 shared Andrew V. AnzaloneiD· 1 shared Ben K. Wesley· 1 shared Ben S. WittneriD· 1 shared Cem TanrıöveriD· 1 shared D. GulhaniD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

J. Keith JoungORCID

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2 papers

Recent·Most cited

Cancer BiologyProceedings of the National Academy of SciencesPeer-reviewedAug 6, 2025

The E3 ligase HECTD4 regulates COX-2 dependent tumor progression and metastasis

Joanna A. Vuille, Cem Tanrıöver, Ezgi Antmen…·Daniel A. Haber

The paper identifies HECTD4 as a tumor and metastasis suppressor that targets COX-2 for degradation, with COX-2 stabilization driving pro-tumorigenic effects in breast cancer.

5 citations

humanproteomics

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BioinformaticsNature CommunicationsPeer-reviewedFeb 15, 2021

PrimeDesign software for rapid and simplified design of prime editing guide RNAs

Jonathan Y. Hsu, Julian Grünewald, Regan N. Szalay…·Luca Pinello

PrimeDesign is a tool for designing prime editing guide RNAs, enabling single and combination edits, and it supports the creation of a database for over 68,500 pathogenic variants.

190 citationstop 1%

humanCRISPR screen

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