This paper constructs a CITE-seq-based atlas of mouse hematopoietic progenitors, identifying 28 progenitor stages across eight lineages and novel surface markers.

bioRxiv · Sep 12, 2026 · PreprintImmunology

CITE-seq of murine bone marrow plasmacytoid dendritic cells and haematopoietic progenitor cells in sepsis

Johannes Andreas Korfhage, Elena Siakaeva, Mahamudul Hasan Bhuyan, Bettina Budeus, Dimitris Ttoouli, Tobias Lautwein, Stefanie B. Flohé, Stefanie Scheu

The paper provides CITE-seq data of bone marrow cells from septic and sham mice to study transcriptional and surface marker changes in sepsis.

bioRxiv · Jul 21, 2026 · PreprintImmunology

Artificial Soil (ArtSoil): recreating soil conditions in synthetic plant growth media

Vera Kaplunova, Houda Alioui, Tobias Griguschies, Luca Müller, Vivien Joisten-Rosenthal, Tobias Lautwein, Sabine U Metzger, Paloma Durán, Eliza P.I. Loo

The paper introduces ArtSoil, a synthetic growth medium that mimics soil conditions for plants, enabling microbiota-driven growth without sugar supplementation and supporting physiologically relevant plant development.

The Plant Journal · Mar 30, 2026Peer-reviewedPlant Biology

Imputation integrates single-cell and spatial gene expression data to resolve transcriptional networks in barley shoot meristem development

Edgar Demesa-Arévalo, Hannah Dörpholz, Isaia Vardanega, Jan Eric Maika, Itzel Pineda-Valentino, Stella Eggels, Tobias Lautwein, Karl Kӧhrer, Thorsten Schnurbusch, Maria von Korff, Björn Usadel, Rüdiger GW Simon

Nature Plants · Jan 7, 2026Peer-reviewedPlant Biology

Defining the cardiac fibroblast secretome in the healthy and infarcted mouse heart

Jasmin Bahr, Gereon Poschmann, Andreas Jungmann, Martin Busch, Zhaoping Ding, Jens Vogt, Ria Zalfen, Julia Steinhausen, Arlen Aurora Euan Martínez, Thorsten Wachtmeister, Daniel Rickert, Tobias Lautwein, Christina Alter, Junedh Amrute, Kory J. Lavine, , Jürgen Schrader

This study identifies the secretome of cardiac fibroblasts in healthy and infarcted mouse hearts, revealing dynamic paracrine factors and potential biomarkers or therapeutic targets.

Communications Biology · Apr 29, 2025Peer-reviewedPhysiology

Linker histone H1-0 is a specific mediator of the repressive ETV6::RUNX1 transcriptional landscape

Vera Helena Jepsen, Andrea Hänel, Daniel J. Picard, Rigveda Bhave, Rebecca Hasselmann, Juha Mehtonen, Julian Schliehe‐Diecks, Carla‐Johanna Kath, Vithusan Suppiyar, Yash Prasad, Katerina Schaal, Jia‐Wey Tu, Nadine Rüchel, Ersen Kameri, Nan Qin, , Ute Fischer

This study identifies H1-0 as a mediator of ETV6::RUNX1-induced quiescence in BCP-ALL preleukemic cells and suggests HDACi treatment as a potential therapeutic approach.

HemaSphere · Apr 1, 2025Peer-reviewedCancer Biology

Host-parasite interactions of an avian blood parasite elucidated by single-cell transcriptomics

Tim Maximilian Rapp, Tobias Lautwein, Robert Peuß, Joachim Kurtz, Oliver Krüger, Nayden Chakarov

The paper uses single-cell RNA sequencing to study host-parasite interactions in an avian blood parasite, revealing immune evasion strategies and immunosuppression by the parasite.

bioRxiv · Mar 14, 2025 · PreprintEcology

Complete sequences of six Major Histocompatibility Complex haplotypes, including all the major MHC class II structures

Torsten Houwaart, Stephan Scholz, Nicholas R. Pollock, William Hunt Palmer, Katherine M. Kichula, Daniel Rodrigo Strelow, Duyen Bao Le, Dana Belick, Lisanna Hülse, Tobias Lautwein, Thorsten Wachtmeister, Tassilo Erik Wollenweber, Birgit Henrich, Karl Köhrer, Peter Parham, , Alexander Dilthey

The paper completes six MHC haplotypes, including DR1, DR4, and structurally variable C4 regions, improving reference panels for immunogenomics analysis.

HLA · Mar 18, 2023Peer-reviewedGenomics