Ajeet Kumar

This study investigates the role of H3R in DRG neurons and shows that an H3R inverse agonist reduces mechanical hypersensitivity in neuropathic pain without affecting thermal pain.

The paper develops a DART platform to selectively modulate GABAA receptor subunits using neurosteroids, identifying C11-linked compounds that enhance GABA currents in 4/{delta}-containing receptors.

The paper investigates the range of actions of neurosteroid analogues using in silico and in vitro methods, revealing unexpected modulation of multiple targets beyond GABA-A receptors.

The paper identifies mossy cell hypo-excitability in FXS due to increased Kv7 function and shows that circuit-based Kv7 inhibition normalizes dentate output.

The paper identifies chromatin accessible sites and transcription factors in RGCs that correlate with axon growth capacity and shows CREB overexpression promotes axon regeneration.