Author

Jean Michel Dela Vedova-Costa

Universidade Federal do ParanáORCID 0000-0002-5656-7239Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 1 Organism:human· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Achille BroggiiD· 1 shared Andreas ZanzoniiD· 1 shared Bastien MorletiD· 1 shared Charlene Gaedke· 1 shared Christine BruniD· 1 shared Élodie MonsellieriD· 1 shared Eric MartíneziD· 1 shared Fabien DurbessoniD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperSystems Biology

Achille BroggiORCID

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1 paper

Recent·Most cited

A quantitative interactome map reveals affinity tailored hijacking of human cellular functions by resident and pathogenic bacteria

Jaime Fernandez-Macgregor, Laura Ilari, Fabien Durbesson, Stéphane Audebert, Luc Camoin, Bastien Morlet, Virginie Millet, Jean Michel Dela Vedova-Costa, Charlene Gaedke, Vincent Kourilsky, Lou Bergogne, Eric Martínez, Achille Broggi, Jean‐Paul Borg, Søren Østergaard, , Renaud Vincentelli

The paper reports a large-scale quantitative interactome of human PDZ domains and bacterial PDZ-binding motifs, showing bacteria tailor effector sequences to bind with similar or higher affinity than human PBMs to hijack host functions.

bioRxiv · Oct 5, 2026 · PreprintSystems Biology