Mitotic chromosome condensation resets chromatin to maintain transcriptional homeostasis
Lucía Ramos-Alonso, Petter Holland, Stéphanie Le Gras, Xu Zhao, Bernard Jost, Magnar Bjørås, Yves Barral, Jorrit M. Enserink, Pierre Chymkowitch
The paper shows that mitotic chromosome condensation resets transcriptional homeostasis by preventing unscheduled gene expression and transcriptional drift in the subsequent interphase.
Proceedings of the National Academy of Sciences · Jan 19, 2023Peer-reviewedMolecular Biology