Nevena Cvetešić

Liver kinase B1 (LKB1) regulates the epigenetic landscape of mouse pancreatic beta cells

This study shows that LKB1 deletion in mouse pancreatic beta cells causes widespread chromatin accessibility changes and affects gene expression, including neuronal genes.

TBPL2/TFIIA complex establishes the maternal transcriptome by an oocyte-specific promoter usage

The paper shows that the TBPL2/TFIIA complex establishes the oocyte transcriptome by using a specific TSS recognition code through oocyte-specific promoter usage.

Conservative route to extreme genome compaction in a miniature annelid

The paper decodes the compact genome of Dimorphilus gyrociliatus, revealing a conservative route to genome compaction with features similar to vertebrates.

Global regulatory transitions at core promoters demarcate the mammalian germline cycle

The paper identifies global regulatory transitions at core promoters during mammalian germline development, showing a shift from somatic to maternal promoter codes in oogenesis.

Zebrafish embryonic tissue differentiation is marked by concurrent cell cycle dynamic and gene promoter regulatory changes

The paper shows that during zebrafish embryonic development, core promoter architecture changes correlate with cell cycle dynamics and lineage-specific gene expression.

Saccharomyces cerevisiae displays a stable transcription start site landscape in multiple conditions

The paper shows that the transcription start site landscape in Saccharomyces cerevisiae remains stable across different environmental conditions and identifies a negative correlation between TSS shape index and expression levels.

SLIC-CAGE: high-resolution transcription start site mapping using nanogram-levels of total RNA

SLIC-CAGE enables high-resolution transcription start site mapping using nanogram-level total RNA, significantly reducing the required input compared to existing CAGE methods.