Søren Warming

The paper uses Sleeping Beauty mutagenesis to identify BACH2 and other genes that enhance CD8+ T cell persistence and function under chronic antigen stimulation, improving engineered T cell therapies.

The paper identifies Grem1-expressing fibroblastic reticular cells as a source of FLT3L that supports dendritic cell homeostasis and function in lymph nodes.

This paper develops a degron-modified Cas12a system to enable accurate single-cell detection of pre-crRNAs, enhancing Perturb-seq capabilities for multiplex guide expression.

This paper introduces a method to degrade proteins using small tags and an artificial bacterial E3 ligase, demonstrating its effectiveness in neurons and mouse brains.

This study investigates the role of Zfp423 in cerebellar neurogenesis, revealing its domain-specific effects on cell cycle progression, DNA damage response, and Purkinje cell development in mouse models.